biology

Series: Microbiome Revolution | Part: 5 of 8 Primary Tag: FRONTIER SCIENCE Keywords: microbiome, immune system, hygiene hypothesis, autoimmune disease, gut immunity, tolerance In the early 1980s, a pediatric allergist named David Strachan noticed something strange in British health records. Children with more older siblings had lower rates of hay fever.

Series: Longevity Science | Part: 1 of 7 Primary Tag: FRONTIER SCIENCE Keywords: hallmarks of aging, López-Otín, genomic instability, telomere attrition, epigenetic alterations, longevity In 2013, a paper appeared in Cell that would reshape the entire field of aging research. Carlos López-Otín and colleagues proposed something audacious: a unified framework for

Series: Longevity Science | Part: 2 of 7 Primary Tag: FRONTIER SCIENCE Keywords: aging, disease, programmed aging, damage accumulation, David Sinclair, longevity Here's a question that sounds philosophical but has enormous practical implications: Is aging a disease? If aging is just normal biology—the natural course of life—then

The Biology of Why We Age—And Whether We Have to For most of human history, aging was fate. You were born, you grew, you declined, you died. The trajectory was fixed. The timeline might vary—disease, accident, fortune—but the direction never did. Entropy always won. That story is

Series: Microbiome Revolution | Part: 8 of 8 Primary Tag: FRONTIER SCIENCE Keywords: microbiome, holobiont, coherence, ecosystem, health, symbiosis Walt Whitman wrote, "I contain multitudes." He meant it philosophically. He didn't know how literally true it was. You are 37 trillion human cells and 38 trillion bacterial

In 1864, French physiologist Paul Bert stitched two rats together. Not metaphorically. He surgically joined them so they shared a circulatory system—blood flowing from one animal into the other and back. He called it parabiosis, from the Greek for "living beside." Bert was interested in physiology, not