biology

Harvard's David Sinclair takes NMN every morning based on his theory that aging is a loss of epigenetic information, not irreversible damage. NAD+ and sirtuin proteins are central to his framework — and to a fierce scientific debate.

Senescent cells are biological zombies: they've stopped dividing but linger in tissues, leaking inflammatory signals that damage neighboring cells. Senolytic drugs can selectively clear them — and in mice, the results are striking.

The goal was never just more years — it was more good years. Healthspan science identifies the cellular and molecular processes behind decline, and increasingly has interventions that move the needle on both.

The Longevity Gold Rush: Billionaires Betting on Reversing Aging Series: Longevity Science | Part: 6 of 7 Primary Tag: FRONTIER SCIENCE Keywords: Altos Labs, Calico, longevity companies, Jeff Bezos, Google, anti-aging, biotech Why Now? Longevity research has existed for decades. Why did it suddenly become attractive to billionaires? Scientific momentum: The

In 1961, Leonard Hayflick discovered that human cells have a division limit. The counter turns out to be your telomeres — chromosome end-caps that fray a little each time your DNA replicates. When they run out, the cell stops.

Emily Whitehead was 6 years old and out of options when she became the first child treated with CAR-T therapy. Her engineered T cells eliminated her leukemia. The science behind that result is one of the most remarkable in modern medicine.