biology

Series: New Immunology | Part: 2 of 8 Primary Tag: FRONTIER SCIENCE Keywords: V(D)J recombination, clonal selection, somatic hypermutation, affinity maturation, immune memory Here's something that should genuinely blow your mind: your immune system runs a compressed version of evolution inside your body. Every day. Not metaphorically.

Your Immune System Is Smarter Than You Think—And We're Only Now Learning Its Language For most of the 20th century, immunology was a war story. Invaders and defenders. Pathogens and antibodies. The immune system was cast as the body's military—trained to identify enemies, mount

Series: New Immunology | Part: 3 of 8 Primary Tag: FRONTIER SCIENCE Keywords: trained immunity, BCG vaccine, innate immune memory, epigenetics, monocytes, macrophages For decades, immunology had a clean division: innate immunity is fast but doesn't learn; adaptive immunity is slow but remembers. The textbooks were clear. The T

Series: New Immunology | Part: 4 of 8 Primary Tag: FRONTIER SCIENCE Keywords: checkpoint inhibitors, PD-1, CTLA-4, cancer immunotherapy, James Allison, Tasuku Honjo, Nobel Prize In the 1990s, two researchers—working independently, on different continents—discovered something that would transform cancer treatment. Their discoveries weren't about killing cancer cells

Your Body Runs on Electricity—And It Matters More Than You Think Here's something you probably didn't learn in biology class: every cell in your body maintains an electrical voltage across its membrane. Not just neurons—every cell. Your skin cells, your liver cells, your stem

Series: New Immunology | Part: 8 of 8 Primary Tag: FRONTIER SCIENCE Keywords: immunology, systems biology, information processing, coherence, self-recognition We've traveled through the immune system: from the ancient innate responses to the learning adaptive system, from trained immunity to cancer immunotherapy, from the gut-immune axis to neuroinflammation. The