ideasthesia

Sign in Subscribe

science

Token-space geometry, organoid intelligence, constructor theory, active inference frontiers — where silicon and biology begin to share the same manifold. Explore the lattice → [M=T/C](/tag/m-t-c/) • [Theory](/tag/atom-theory/) • [Neurodiversity](/tag/neurodiversity/)

Lifespan vs. Healthspan: A Synthesis

Lifespan vs. Healthspan: A Synthesis

Series: Longevity Science | Part: 7 of 7 Primary Tag: FRONTIER SCIENCE Keywords: healthspan, lifespan, longevity, aging, quality of life, compression of morbidity Here's a question that doesn't get asked enough in longevity science: Why do we want to live longer? The obvious answer—more time—isn&

The Longevity Gold Rush: Billionaires Betting on Reversing Aging

The Longevity Gold Rush: Billionaires Betting on Reversing Aging

Series: Longevity Science | Part: 6 of 7 Primary Tag: FRONTIER SCIENCE Keywords: Altos Labs, Calico, longevity companies, Jeff Bezos, Google, anti-aging, biotech In January 2022, a new biotech company launched with $3 billion in funding—the largest initial funding in biotech history. It recruited Nobel laureates, poached top researchers from

Telomeres and the Hayflick Limit: Your Cells Can Only Divide So Many Times

Telomeres and the Hayflick Limit: Your Cells Can Only Divide So Many Times

Series: Longevity Science | Part: 4 of 7 Primary Tag: FRONTIER SCIENCE Keywords: telomeres, Hayflick limit, telomerase, Elizabeth Blackburn, cellular aging, replicative senescence In 1961, Leonard Hayflick made a discovery that nobody wanted to believe. He was trying to grow human cells in culture, and they kept dying. This shouldn'

CAR-T Therapy: Engineering Cancer Killers

CAR-T Therapy: Engineering Cancer Killers

In 2012, a six-year-old girl named Emily Whitehead was dying of leukemia. She had relapsed twice after chemotherapy. There were no more standard options. Her doctors at the Children's Hospital of Philadelphia tried something that had never worked before: they extracted her T cells, genetically modified them to

The Two Arms of Immunity: Fast and Slow, General and Specific

The Two Arms of Immunity: Fast and Slow, General and Specific

Series: New Immunology | Part: 1 of 8 Primary Tag: FRONTIER SCIENCE Keywords: innate immunity, adaptive immunity, immune response, T cells, B cells, inflammation Your immune system has a problem: it needs to protect you from threats it has never seen before. Think about what this means. A virus that has

How Your Immune System Learns: Evolution Running in Real Time

How Your Immune System Learns: Evolution Running in Real Time

Series: New Immunology | Part: 2 of 8 Primary Tag: FRONTIER SCIENCE Keywords: V(D)J recombination, clonal selection, somatic hypermutation, affinity maturation, immune memory Here's something that should genuinely blow your mind: your immune system runs a compressed version of evolution inside your body. Every day. Not metaphorically.

The New Immunology

The New Immunology

Your Immune System Is Smarter Than You Think—And We're Only Now Learning Its Language For most of the 20th century, immunology was a war story. Invaders and defenders. Pathogens and antibodies. The immune system was cast as the body's military—trained to identify enemies, mount